ʻO (1-3)-β-D-glucan ka loulou nalo mai ka ʻaoʻao o ka moe i ka hoʻomaʻamaʻa mua ʻana o ka invasive.

ʻO ka candidiasis invasive kahi pilikia e hoʻoweliweli pinepine i ke ola i nā maʻi maʻi maʻi.ʻO ka hoʻomaʻamaʻa mua ʻana i ukali ʻia e ka hoʻomaʻamaʻa wikiwiki ʻana i ka hoʻomaikaʻi ʻana i ka hopena ma o ka hōʻemi ʻana i ka hoʻohana antifungal pono ʻole he mea paʻakikī nui i ka hoʻonohonoho ICU.ʻO ke koho ʻana i ka mea maʻi i ka manawa he hana koʻikoʻi no ka hoʻokele maʻi a me ka hoʻokele waiwai.ʻO nā ala e hui pū ai i nā mea pilikia olakino a me ka ʻikepili colonization Candida i hoʻomaikaʻi i ko mākou hiki ke ʻike mua i kēlā mau maʻi.ʻOiai ʻo ka waiwai wānana maikaʻi ʻole o nā helu a me nā lula wānana a hiki i 95 a 99%, ʻoi aku ka haʻahaʻa o ka waiwai wānana maikaʻi, ma waena o 10 a 60%.No laila, inā hoʻohana ʻia kahi helu maikaʻi a i ʻole ka lula e alakaʻi i ka hoʻomaka ʻana o ka lāʻau antifungal, hiki ke mālama ʻia nā mea maʻi he nui ʻole.Hōʻike nā biomarkers Candida i nā waiwai wānana maikaʻi aʻe;akā naʻe, nele lākou i ka noʻonoʻo a no laila ʻaʻole hiki ke ʻike i nā hihia āpau o ka candidiasis invasive.ʻO ka (1-3)-β-D-glucan (BG) assay, kahi hoʻāʻo antigen panfungal, ua ʻōlelo ʻia ma ke ʻano he mea kōkua no ka ʻike ʻana i nā mycoses invasive i nā maʻi hemato-oncological kiʻekiʻe.ʻO kāna kuleana i ka heluna kanaka ICU nui aʻe e wehewehe ʻia.Pono nā hoʻolālā koho lapaʻau maikaʻi i hui pū ʻia me nā mea hana hoʻokolohua hana i mea e mālama ai i nā maʻi kūpono i ka manawa kūpono ma o ka mālama ʻana i nā kumukūʻai o ka nānā ʻana a me ka lāʻau lapaʻau i ka haʻahaʻa.ʻO ke ala hou i manaʻo ʻia e Posteraro a me nā hoa hana ma ka puke mua o Critical Care e hoʻokō i kēia mau koi.ʻO kahi waiwai BG maikaʻi hoʻokahi i nā maʻi maʻi i hoʻokomo ʻia i ka ICU me ka sepsis a manaʻo ʻia e noho ʻoi aku ma mua o 5 mau lā ma mua o ka palapala o ka candidemia e 1 a 3 mau lā me ka pololei diagnostic ʻike ʻole.ʻO ka hoʻohana ʻana i kēia kānana fungal helu hoʻokahi ma kahi ʻāpana i koho ʻia o nā mea maʻi ICU me ka 15 a 20% ka pilikia o ka hoʻomohala ʻana i ka candidemia he ala ʻoluʻolu a hiki ke uku.Inā hōʻoia ʻia e nā noiʻi multicenter, a hoʻonui ʻia i nā poʻe maʻi ʻokiʻoki i ka nui o ka pilikia o ka candidiasis invasive ma hope o ke kaʻina ʻana o ka ʻōpū, ʻo kēia ala Bayesian-based stratification stratification i manaʻo ʻia e hoʻonui i ka maikaʻi o ka lāʻau lapaʻau ma o ka hōʻemi ʻana i ka hoʻohana waiwai mālama ola hiki ke maʻalahi i ka mālama ʻana i nā maʻi maʻi koʻikoʻi i ka pilikia. o ka candidiasis invasive.